Multiaxial Biophysical Control of Oncogenic Phase Separation by Indoleamines: A Proof-of-Concept Synthesis of Landscape-Level Regulation
Doris Loh, Luiz Gustavo de Almeida Chuffa, Fábio Rodrigues Ferreira Seiva, Russel Joseph Reiter
The paper identifies a network of 26 genes at the intersection of melatonin signaling and phase separation, showing melatonin suppresses oncogenic drivers and correlates with poorer survival in breast and gastric cancers.
Journal of Pineal Research · Jun 17, 2026Peer-reviewedCancer Biology