Minghao Du

TEITbase: a database for transposable element (TE)-initiated transcripts in human cancers

The paper develops TEITbase, a database of TE-initiated transcripts in 33 cancer types, identifying 38,995 transcripts and 6,203 tumor-specific ones, with tools for downstream analysis.

Common Signatures of Neutrophils in Diverse Disease Conditions

The paper identifies two distinct neutrophil clusters with unique immune features across diverse disease conditions in mouse models.

The Genomes of Nematode-Trapping Fungi Provide Insights into the Origin and Diversification of Fungal Carnivorism

This study compares the genomes of nematode-trapping fungi and non-NTF to identify genomic changes linked to carnivorism and adaptation to post-Permian-Triassic extinction environments.

Functional diversification of the MADS-box gene family in fine-tuning the dimorphic transition of Talaromyces marneffei

The paper identifies functional diversification of MADS-box genes in Talaromyces marneffei, showing mads9 inhibits hyphal-to-yeast transition while mads10 does not.

Transposable elements drive species-specific and tissue-specific transcriptomes in human development

The paper identifies TE-initiated transcripts across human tissues and embryonic stem cells, showing tissue-specific activation and primate-specific TSSs contributing to gene regulation.

Species-specific circular RNA circDS-1 enhances adaptive evolution in Talaromyces marneffei through regulation of dimorphic transition and virulence

This study identifies circDS-1, a circular RNA in Talaromyces marneffei, that promotes dimorphic transition and virulence, revealing a novel mechanism for fungal thermal adaptation.

circFL-seq reveals full-length circular RNAs with rolling circular reverse transcription and nanopore sequencing

The paper introduces circFL-seq, a method for full-length circRNA sequencing using RCRT and nanopore sequencing, identifying 77,606 high-quality circRNAs from human cell lines and tissues.