Author

Jing Hui Yang

Peking UniversityORCID 0000-0002-2048-735XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ariana ArceiD· 1 shared Di WuiD· 1 shared Dingbao CheniD· 1 shared Ence YangiD· 1 shared Fuhai LiuiD· 1 shared Gang WangiD· 1 shared Guoqiang LiuiD· 1 shared Han ZhaoiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

Ariana ArceORCID

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3 papers

Recent·Most cited

CDH3 as a Novel Therapeutic Target in Basal-like Double-Negative Prostate Cancer

Guoqiang Liu, Shiyu Wang, Loan Duong, Ziyu Zeng, Jing Hui Yang, Yun Zhao, Sharif Rahmy, Shan Feng, Ariana Arce, Lin Jia, Jun Wan, Liang Cheng C, Xuemin Lu, Xin Lü

This study identifies CDH3 as a key driver of basal-like prostate cancer and shows that CDH3-targeted therapies like ADCs and CAR T cells are effective in preclinical models.

bioRxiv · Nov 18, 2025 · PreprintCancer Biology

Common Signatures of Neutrophils in Diverse Disease Conditions

Di Wu, Ying Jun Cao, Hongjie Chen, Minghao Du, Tingting Wang, Jiarui Zhao, Mengyuan Li, Wenjing Wu, Huixuan Zhang, Ence Yang, Jing Hui Yang, Jian Chen

The paper identifies two distinct neutrophil clusters with unique immune features across diverse disease conditions in mouse models.

Cell Discovery · Aug 1, 2025Peer-reviewedImmunology

Estrogen Receptor 1 Signaling in Hepatic Stellate Cells Designates Resistance to Liver Fibrosis

Tianhao Li, Gang Wang, Han Zhao, Fuhai Liu, Zhangyuzi Deng, Dingbao Chen, Xin Zhou, Ying Cao, Wei Fu, Haoyue Zhang, Jing Hui Yang

This study shows that estrogen receptor 1 in hepatic stellate cells influences liver fibrosis severity, with ESR1 deletion promoting fibrosis and estradiol reducing it in mice.

Cell Discovery · Apr 15, 2025Peer-reviewedPathology