Author

Giannoula Lakka Klement

ORCID 0000-0002-7479-2798Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Edward A. RietmaniD· 3 shared Jack A. TuszyńskiiD· 2 shared Alex Bloemendal· 1 shared Elizabeth J. Brant· 1 shared Giulia Pozzati· 1 shared Hananel HazaniD· 1 shared Hava T. SiegelmanniD· 1 shared Jack A. Tuszynski· 1 shared

Activity by Year

2015-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersSystems Biology

Edward A. RietmanORCID

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3 papers

Recent·Most cited

Systems BiologyOncoPeer-reviewedAug 6, 2024

A Systems Biology Analysis of Chronic Lymphocytic Leukemia

Giulia Pozzati, Jinrui Zhou, Hananel Hazan…·Jack A. Tuszyński

This paper identifies key proteins in CLL using statistical thermodynamics and systems biology, advocating for multi-target inhibition strategies to improve therapy design.

3 citations

humanwhole-genome sequencing

𝕏 PostBluesky

Systems BiologyPLoS ONEPeer-reviewedMar 19, 2020

Personalized Therapy Design for Systemic Lupus Erythematosus Based on the Analysis of Protein-Protein Interaction Networks

Elizabeth J. Brant, Edward A. Rietman, Giannoula Lakka Klement…·Jack A. Tuszyński

The paper analyzes protein expression data from Lupus patients to identify key proteins in their interaction networks and suggests potential drug targets.

6 citations

humanproteomics

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Cancer BiologybioRxivPreprintJul 13, 2015

Gibbs Free Energy of Protein-Protein Interactions Reflects Tumor Stage

Edward A. Rietman, Alex Bloemendal, John Platig…·Giannoula Lakka Klement

The paper correlates Gibbs free energy of protein-protein interactions with tumor stage and 5-year survival in cancer patients.

DOI 10.1101/022491

humanproteomics

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