Auto-regulation of the real-time kinetics of the human mitochondrial replicative helicase
Ismael Plaza-G.A., María Ortiz-Rodríguez, Seth P. Buchanan, Samuel Miguez-Amil, Kateryna M. Lemishko, Fernando Moreno‐Herrero, Rafael Fernández-Leiro, Grzegorz L. Ciesielski, Borja Ibarra
This study investigates the real-time kinetics of Twinkle, a human mitochondrial helicase, and identifies regulatory roles of its N-terminal ZBD and C-terminal tail, along with mtSSB interactions.
Nature Communications · Jul 1, 2025Peer-reviewedBiophysics