Anil Mukund Limaye

The CYP1A1 connection between enterolactone and breast cancer risk

This study shows enterolactone reduces CYP1A1 mRNA expression in breast cancer cells by antagonizing AHR, while increasing CYP1A1 protein through ER, potentially lowering breast cancer risk.

Expression of MMP-11, an estrogen-suppressed gene in MCF-7 cells, is elevated upon acquisition of tamoxifen resistance

This study shows that estrogen suppresses MMP-11 in MCF-7 cells, but tamoxifen resistance leads to increased MMP-11 expression, suggesting a role in drug resistance and tumor aggressiveness.

Proliferative response of ERalpha-positive breast cancer cells to 10 uM enterolactone, and the associated alteration in the transcriptomic landscape.

This study investigates the proliferative effect of 10 μM enterolactone on ER-positive breast cancer cells and identifies transcriptomic changes associated with this response.