Racquel Domingo-Gonzalez

The paper uses single-cell transcriptomics and in-situ imaging to study lung mesenchymal cell diversity during development and hyperoxia, finding delayed diversity and emergence of Acta1+ cells under hyperoxic conditions.

The paper profiles the transcriptional development and injury sensitivity of lung endothelial subtypes during postnatal growth, revealing distinct transcriptomic changes and differential responses to hyperoxia.

The paper identifies TGFBI as a protein promoting NF-kappa-B mediated angiogenesis during early lung development by enhancing nitric oxide production.

This study uses single-cell transcriptomics to reveal diverse immune cell roles in the developing mouse lung, showing dynamic changes in macrophage subtypes and their functions during lung development.