Author

Gonzalo G. Guendulain

ORCID 0000-0002-7497-5455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Ana Lis MoyanoiD· 1 shared David Campo‐CaballeroiD· 1 shared David OtaeguiiD· 1 shared Hirune Crespillo-Velasco· 1 shared Rocío del Carmen Bravo-MianaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Ana Lis MoyanoORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintOct 28, 2026

Detergent lysis controls are critical for single extracellular vesicle phenotyping in SP-IRIS platforms

Gonzalo G. Guendulain, David Otaegui, Hirune Crespillo-Velasco…·Ana Lis Moyano

This study identifies a critical technical limitation in SP-IRIS/IF platforms where non-vesicular artifacts persist after detergent treatment, highlighting the need for detergent lysis controls to ensure accurate single-EV phenotyping.

DOI 10.64898/2026.10.23.760472

humanspatial transcriptomics

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