Xena Marie Mapel

This study identifies a QTL on chromosome 4 associated with circadian feeding rhythmicity in pigs, linking it to genes involved in feeding behavior and energy homeostasis.

This study identifies lactation-stage specific QTL for milk urea concentration in dairy cattle breeds, highlighting pleiotropic effects and candidate genes.

The paper identifies molecular QTL enriched for structural variants in a cattle long-read sequencing cohort, showing SVs have a significant impact on gene expression and splicing.

The paper identifies a structural variant upstream of KIT associated with facial depigmentation in white-headed cattle using pangenome analysis and long-read sequencing.

The paper shows RNA sequencing variants in cattle tissues are enriched for eQTL, with 75% of eGenes detected and a 2-fold enrichment compared to DNA sequencing variants.

The paper presents a high-quality wisent genome assembly, identifies a deletion inactivating the THRSP gene, and shows its absence in bison compared to cattle and water buffalo.

This study uses a pangenome to genotype structural variation in cattle, improving e/sQTL mapping by identifying 92 structural variants as causal for eQTL and 73 for sQTL.

The paper identifies 41k regulatory loci in cattle reproductive tissues linked to male fertility by analyzing gene expression and splicing variation across testis, epididymis, and vas deferens.

The paper compares three pangenome construction methods, showing their impact on variant representation and analysis in a bovine super-pangenome.

The paper identifies a 1-bp deletion in QRICH2 as a recessive cause of low sperm count and immotile sperm with morphological abnormalities in Brown Swiss bulls.

The paper quantifies evolutionary constraint on intronic branch point sequences in bovine and human genomes, finding strong purifying selection and links to alternative splicing.