Author

Richard Hardstone

Harvard UniversityORCID 0000-0002-7502-9145Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Assay:electronic health records· 4 Research Focus:benchmarking· 3 Approach:statistical model· 3 Research Focus:batch correction / integration· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Sydney S. CashiD· 3 shared Angelique Christine PaulkiD· 2 shared Charlie WindolfiD· 2 shared Domokos MeszénaiD· 2 shared Erdem VaroliD· 2 shared Eric M. TrautmanniD· 2 shared Irene CapraraiD· 2 shared Julien BoussardiD· 2 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Sydney S. CashORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

E/I ratio and net E+I strength are differentially affected across brain disorders

Arthur-Ervin Avrămiea, Marina Diachenko, Andrew Westbrook, Richard Hardstone, Huibert D. Mansvelder, Hilgo Bruining, Klaus Linkenkaer‐Hansen

The paper develops computational models to analyze E/I ratio and E+I strength in brain disorders, finding distinct patterns in epilepsy, Alzheimer's, autism, and ADHD.

bioRxiv · Aug 15, 2025 · PreprintNeuroscience

DREDge: robust motion correction for high-density extracellular recordings across species

Charlie Windolf, Han Young Yu, Angelique Christine Paulk, Domokos Meszéna, William Muñoz, Julien Boussard, Richard Hardstone, Irene Caprara, Mohsen Jamali, Yoav Kfir, Duo Xu, Jason E. Chung, Kristin K. Sellers, Zhiwen Ye, Jordan R Shaker, , Erdem Varol

DREDge improves motion correction in high-density extracellular recordings across species, enhancing reliability and reducing errors in electrophysiological data.

Nature Methods · Mar 6, 2025Peer-reviewedNeuroscience

EEG-VLM Toolbox: Extending voxel-based lesion mapping to multi-dimensional EEG data

Richard Hardstone, Lauren M. Ostrowski, Aliceson Nicole Dusang, Eduardo López‐Larraz, Jessica Jesser, Sydney S. Cash, Steven C. Cramer, Leigh R. Hochberg, Ander Ramos‐Murguialday, David J. Lin

The paper introduces EEG-VLM, a method to map neuroanatomical lesions to multidimensional EEG data, finding frontal subcortical white matter lesions correlate with reduced parietal EEG responses.

bioRxiv · Oct 25, 2024 · PreprintNeuroscience

Robust online multiband drift estimation in electrophysiology data

Charlie Windolf, Angelique Christine Paulk, Yoav Kfir, Eric M. Trautmann, Samuel Garcia, Domokos Meszéna, William Muñoz, Richard Hardstone, Irene Caprara, Mohsen Jamali, Julien Boussard, Ziv M. Williams, Sydney S. Cash, Liam Paninski, Erdem Varol

This paper introduces DREDge, an algorithm for robust online drift estimation in electrophysiology data, improving scalability and temporal resolution for human and mouse recordings.

IEEE International Conference on Acoustics Speech and Signal Processing · May 5, 2023Peer-reviewedNeuroscience

Frequency-specific neural signatures of perceptual content and perceptual stability

Richard Hardstone, Matthew W. Flounders, Michael Zhu, Biyu Jade He

The paper identifies frequency-specific neural signatures in MEG data that distinguish perceptual content from perceptual stability during bistable perception.

eLife · Sep 20, 2022Peer-reviewedNeuroscience