Author

Carlos Copana

Purdue University West LafayetteORCID 0000-0002-7510-0634Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Bingxin ZhaoiD· 2 shared Bingxuan LiiD· 2 shared Juan ShuiD· 2 shared Xiaochen YangiD· 2 shared Yujue Li· 2 shared Zirui FaniD· 2 shared Bowei Xi C· 1 shared Fei XueiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Bingxin ZhaoORCID

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2 papers

Recent·Most cited

Inferring Multi-Organ Genetic Causal Connections using Imaging and Clinical Data through Mendelian Randomization

Juan Shu, Rong Zheng, Julio A. Chirinos, Carlos Copana, Bingxuan Li, Zirui Fan, Xiaochen Yang, Yilin Yang, Xiyao Wang, Yujue Li, Bowei Xi C, Tengfei Li, Hongtu Zhu B, Bingxin Zhao

This study uses Mendelian randomization to identify genetic causal links between 58 diseases, 56 imaging traits, and multiple organs across 402 imaging traits and 372 clinical outcomes.

Nature Biomedical Engineering · Nov 19, 2025Peer-reviewedGenetic & Genomic Medicine

Analyzing bivariate cross-trait genetic architecture in GWAS summary statistics with the BIGA cloud computing platform

Yujue Li, Fei Xue, Bingxuan Li, Yilin Yang, Zirui Fan, Juan Shu, Xiaochen Yang, Xiyao Wang, Jinjie Lin, Carlos Copana, Bingxin Zhao

The paper introduces BIGA, a cloud platform for analyzing cross-trait genetic architecture using GWAS summary statistics, enabling unified data analysis and resource sharing.

bioRxiv · Apr 28, 2023 · PreprintGenetics