Author
Tengfei Li
University of North Carolina at Chapel HillORCID 0000-0001-6142-3865Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2018-2026 · peak 5/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author linksMutual co-authors in cluster
21 papers
Recent·Most cited
- Developmental BiologybioRxivPreprint
Microbes on the Mind: Multi-modal Neuroimaging Reveals Gut-Brain Axes in Infants
Tengfei Li, Yue Yang, Seo-Ho Cho…·UNC/UMN Baby Connectome Project Consortium
This study links gut microbiome features to brain development in infants using multimodal neuroimaging and metagenomics.
DOI 10.64898/2026.09.23.753825 - NeuroscienceDevelopmental Cognitive NeurosciencePeer-reviewed
Surface Expansion Regionalization of the Hippocampus in Early Brain Development
Wang Ya, Liangjun Chen, Zhengwang Wu…·Gang Li
The paper explores hippocampal surface expansion patterns in early development using MRI scans, identifying two distinct developmental patterns along different axes.
DOI 10.1016/j.dcn.2026.101733 - NeurosciencebioRxivPreprint
Connectome-based spatial statistics enabling large-scale population analyses of human connectome across cohorts
Tengfei Li, Xifeng Wang, Martin Cole…·Hongtu Zhu B
This paper introduces CBSS, a framework for analyzing structural connectomes across multiple cohorts, showing its reliability and utility in cross-cohort diffusion MRI studies.
DOI 10.64898/2026.04.09.717492 - Genetic & Genomic MedicineNature CommunicationsPeer-reviewed
Computation and resource efficient genome-wide association analysis for large-scale imaging studies
Zhiwen Jiang, Jason L. Stein, Tengfei Li…·Hongtu Zhu B
This paper introduces RVGA, a framework for efficient genome-wide association analysis in imaging genetics, identifying novel loci and genetic correlations in brain structures using UK Biobank data.
2 citationstop 4% - Genetic & Genomic MedicineNature CommunicationsPeer-reviewed
Mapping rare protein-coding variants on multi-organ imaging traits
Yijun Fan, Jie Chen, Zirui Fan…·Bingxin Zhao
The paper identifies rare protein-coding variants associated with multi-organ MRI traits using exome-wide association analysis in the UK Biobank.
- Genetic & Genomic MedicineNature Biomedical EngineeringPeer-reviewed
Inferring Multi-Organ Genetic Causal Connections using Imaging and Clinical Data through Mendelian Randomization
Juan Shu, Rong Zheng, Julio A. Chirinos…·Bingxin Zhao
This study uses Mendelian randomization to identify genetic causal links between 58 diseases, 56 imaging traits, and multiple organs across 402 imaging traits and 372 clinical outcomes.
- Cancer BiologyOncogenePeer-reviewed
Glioma-associated fibroblasts promote glioblastoma resistance to temozolomide through CCL2-CCR2 paracrine signaling
Mingrong Zuo, Shuxin Zhang, Siliang Chen…·Yan‐Hui Liu
This paper shows that glioma-associated fibroblasts enhance glioblastoma resistance to temozolomide by secreting CCL2, which activates the ERK1/2 pathway in cancer cells.
15 citationstop 3% - Genetic & Genomic MedicinemedRxivPreprint
The pivotal role of the X-chromosome in the genetic architecture of the human brain
Zhiwen Jiang, Patrick F. Sullivan, Tengfei Li…·Hongtu Zhu B
The paper investigates the genetic impact of the X-chromosome and sex differences in the human brain, identifying 72 genome-wide significant trait-locus pairs linked to brain-related disorders.
- Genetic & Genomic MedicinemedRxivPreprint
Multi-organ imaging-derived polygenic indexes for brain and body health
Xiaochen Yang, Patrick F. Sullivan, Bingxuan Li…·Bingxin Zhao
The paper uses genetic data to predict imaging-derived phenotypes from the UK Biobank, creating polygenic scores that identify disease risk in external cohorts.
- Genetic & Genomic MedicinemedRxivPreprint
Genetic influences on the shape of brain ventricular and subcortical structures
Bingxin Zhao, Tengfei Li, Xiaochen Yang…·Hongtu Zhu B
The paper identifies 60 genetic loci associated with brain ventricular and subcortical shape features using shape measures from over 45,000 UK Biobank and ABCD study subjects.
- Genetic & Genomic MedicinemedRxivPreprint
The role of sleep in the human brain and body: insights from multi-organ imaging genetics
Zirui Fan, Yilin Yang, Yuxin Guo…·Bingxin Zhao
This study identifies genetic overlaps between sleep traits and multi-organ imaging biomarkers, showing strong genetic links between sleep and psychiatric disorders.
- Developmental BiologybioRxivPreprint
Jointly analyzing the association of human milk nutrients with cognition and temperament traits during the first 6 months of life
Tengfei Li, Tinu Mary Samuel, Ziliang Zhu…·Weili Lin
The paper examines how various human milk nutrients are associated with cognitive and temperament traits in infants up to 18 months old, finding persistent effects of certain nutrients on development.
DOI 10.1101/2022.04.24.489325 - GeneticsNature GeneticsPeer-reviewed
Common variants contribute to intrinsic human brain functional networks
Bingxin Zhao, Tengfei Li, Stephen M. Smith…·Hongtu Zhu B
This study identifies common genetic variants influencing intrinsic brain networks using rsfMRI data from 44,190 individuals, finding associations with cognitive and clinical traits.
- Genetic & Genomic MedicinemedRxivPreprint
Heart-brain connections: phenotypic and genetic insights from 40,000 cardiac and brain magnetic resonance images
Bingxin Zhao, Tengfei Li, Zirui Fan…·Hongtu Zhu B
The paper investigates phenotypic and genetic links between heart and brain using MRI data from 40,000 UK Biobank subjects, finding strong correlations and shared genetic influences.
- Genetic & Genomic MedicinemedRxivPreprint
Genetic influences on the intrinsic and extrinsic functional organizations of the cerebral cortex
Bingxin Zhao, Tengfei Li, Stephen M. Smith…·Hongtu Zhu B
This study identifies genetic loci associated with functional brain networks and areas using large-scale fMRI data, linking them to cognitive traits and brain disorders.
- GeneticsSciencePeer-reviewed
Common genetic variation influencing human white matter microstructure
Bingxin Zhao, Tengfei Li, Yue Yang…·Hongtu Zhu B
This study identifies common genetic variants influencing white matter microstructure using dMRI data from 42,919 individuals, revealing genetic links to neuropsychiatric disorders and other traits.
232 citationstop 1% - GeneticsbioRxivPreprint
Transcriptome-wide association analysis of 211 neuroimaging traits identifies new genes for brain structures and yields insights into the gene-level pleiotropy with other complex traits
Bingxin Zhao, Yue Shan, Yue Yang…·Hongtu Zhu B
This study performs transcriptome-wide association analysis on 211 neuroimaging traits, identifies 204 genes, and shows TWAS-derived polygenic risk scores explain up to 6.97% of phenotypic variance.
5 citations - GeneticsNature GeneticsPeer-reviewed
GWAS of 19,629 individuals identifies novel genetic variants for regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits
Bingxin Zhao, Tianyou Luo, Tengfei Li…·Hongtu Zhu B
This study identifies 287 novel genetic variants associated with brain volumes using GWAS in 19,629 UK Biobank participants and finds genetic correlations with cognitive and mental health traits.
295 citationstop 1% - GeneticsbioRxivPreprint
Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n=17,706)
Bingxin Zhao, Jingwen Zhang, Joseph G. Ibrahim…·Hongtu Zhu B
3 citations - GeneticsCerebral CortexPeer-reviewed
Heritability of regional brain volumes in large-scale neuroimaging and genetic studies
Bingxin Zhao, Joseph G. Ibrahim, Yun Li…·John Hsiao
The paper examines the heritability of regional brain volumes using genetic and neuroimaging data from multiple cohorts, finding high heritability and consistent patterns across populations.