Author

Lauren R Hatfield

Manchester Metropolitan University;ORCID 0000-0002-7513-3014Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:multiple species· 1

Frequent Co-Authors

Dongxu YuaniD· 1 shared Hannah RyaniD· 1 shared Harry WilliamsiD· 1 shared Josie E ParkeriD· 1 shared Mochen DongiD· 1 shared Rémi ZallotiD· 1 shared Yi JiniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Dongxu YuanORCID

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1 paper

Recent·Most cited

CYP123, a sterol C4-methyl oxidase, acts with CYP51 to initiate mycobacterial lanosterol catabolism

Dongxu Yuan, Lauren R Hatfield, Hannah Ryan, Harry Williams, Mochen Dong, Josie E Parker, Yi Jin, Rémi Zallot

This study identifies CYP123 as a key enzyme in mycobacterial lanosterol catabolism, showing it works with CYP51 to oxidize C14-demethylated sterols, expanding the known sterol utilization beyond cholesterol.

bioRxiv · Nov 2, 2026 · PreprintMicrobiology