ImmunologybioRxivPreprint
Optimized antibody with W32I mutation enhances antiviral efficacy against influenza
Shanshan Guan, Qingyu Wang, Jiaojiao Nie…·Yaming Shan
This study optimizes the 3E1 antibody by introducing the W32I mutation, enhancing its antiviral activity against H1N1 and H3N2 by improving binding and reducing steric hindrance.
DOI 10.1101/2025.01.24.634663