Author

Rohan Balakrishnan

University of California San DiegoORCID 0000-0002-7547-8565Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Matteo MoriiD· 2 shared Terence Hwa BiD· 2 shared Zhongge ZhangiD· 2 shared Chenhao WuiD· 1 shared Christina LudwigiD· 1 shared Gabriel ManzanareziD· 1 shared Igor ŠegotaiD· 1 shared Nathan BraniffiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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2 shared papersSystems Biology

Matteo MoriORCID

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2 papers

Recent·Most cited

Principles of gene regulation quantitatively connect DNA to RNA and proteins in bacteria

Rohan Balakrishnan, Matteo Mori, Igor Šegota, Zhongge Zhang, Ruedi H. Aebersold, Christina Ludwig, Terence Hwa B

This study quantifies how gene regulation in E. coli connects DNA to RNA and proteins under growth condition changes, revealing two principles governing protein allocation.

Science · Dec 8, 2022Peer-reviewedSystems Biology

Cellular perception of growth rate and the mechanistic origin of bacterial growth laws

Chenhao Wu, Rohan Balakrishnan, Nathan Braniff, Matteo Mori, Gabriel Manzanarez, Zhongge Zhang, Terence Hwa B

The paper shows that ppGpp in E. coli inversely responds to translational elongation rate, enabling growth rate perception and control through a regulatory circuit.

Proceedings of the National Academy of Sciences · May 11, 2022Peer-reviewedSystems Biology