Dinesh Kumar Gupta

AmpC β-lactamases: A Key to Antibiotic Resistance in ESKAPE Pathogens

The paper reports the first detailed analysis of AmpC β-lactamase distribution, diversity, and evolutionary characteristics in ESKAPE pathogens, highlighting their role in antibiotic resistance.

KODAMA enables self-guided weakly supervised learning in spatial transcriptomics

KODAMA improves spatial transcriptomics analysis by reducing dimensionality while preserving spatial information, showing high accuracy across multiple datasets.

Involvement of translocon complex in hemoglobin import from infected erythrocyte cytoplasm into the Plasmodium parasite

This study identifies PfHDP's role in hemoglobin uptake by Plasmodium parasites and shows its interaction with the translocon complex, suggesting it as a target for antimalarial drugs.

Comparative analysis of codon usage patterns in SARS-CoV-2, its mutants and other respiratory viruses

The paper analyzes codon usage bias in SARS-CoV-2 genomes and compares it with other respiratory viruses to identify evolutionary determinants and adaptation features.

Comparative analyses of SAR-CoV2 genomes from different geographical locations and other coronavirus family genomes reveals unique features potentially consequential to host-virus interaction and pathogenesis

The paper compares SARS-CoV2 genomes from different regions with other coronaviruses to identify unique mutations and host miRNA interactions that may influence viral pathogenesis and host response.

Classification models for Invasive Ductal Carcinoma Progression, based on gene expression data-trained supervised machine learning

The paper develops machine learning models to classify early and late stages of invasive ductal carcinoma using RNA-seq data from 610 patients, and provides a web server for prediction.

ApicoTFdb: The comprehensive web repository of apicomplexan transcription factors and regulators.

ApicoTFdb is a database of transcription factors and regulators in apicomplexan species, including experimentally validated and computationally predicted TFs and TAFs across 14 species.