Author

Inna A. Pyshnaya

Institute of Chemical Biology and Fundamental MedicineORCID 0000-0002-7559-2376Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Ànna PavlovaiD· 1 shared Anne‐Marie Heckel· 1 shared Ivan TarassoviD· 1 shared Mariya I. MeschaninovaiD· 1 shared Natalia NikitchinaiD· 1 shared Nikita ShebanoviD· 1 shared Nina EntelisiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Ànna PavlovaORCID

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1 paper

Recent·Most cited

Modified crRNA variants for precise targeting of point mutations in human mitochondrial DNA by CRISPR-Cas12a

Nikita Shebanov, Anne‐Marie Heckel, Natalia Nikitchina, Ànna Pavlova, Inna A. Pyshnaya, Mariya I. Meschaninova, Ivan Tarassov, Nina Entelis

This study identifies modified crRNA variants for precise targeting of point mutations in human mitochondrial DNA using CRISPR-Cas12a, showing effective discrimination and base editing in vitro and in human cells.

bioRxiv · Sep 13, 2026 · PreprintMolecular Biology