Author

Setsu Endoh‐Yamagami

Fujifilm (Japan)ORCID 0000-0002-7574-750XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H KobayashiiD· 2 shared Hiroshi KatoiD· 2 shared Akira Nabetani· 1 shared Euikyung Shin· 1 shared Kenichi Kazetani· 1 shared Kiyohiro MaedaiD· 1 shared Mitsuho Taniguchi· 1 shared Takashi Wakui· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

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2 shared papersNeuroscience

H KobayashiORCID

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2 papers

Recent·Most cited

NeuroscienceJournal of NeurochemistryPeer-reviewedMar 1, 2026

The tri-culture system reveals an activation cascade from microglia through astrocytes to neurons during neuroinflammation

H Kobayashi, Hiroshi Kato, Mitsuho Taniguchi, Setsu Endoh‐Yamagami

The paper develops a tri-culture system of human neurons, astrocytes, and microglia to study neuroinflammation and reveals a cascade of activation from microglia to astrocytes to neurons.

5 citationstop 2%

humanbulk RNA-seq

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NeurosciencebioRxivPreprintAug 17, 2025

Human aged astrocytes induce neurotoxicity in response to inflammatory stimuli

H Kobayashi, Kiyohiro Maeda, Takashi Wakui…·Setsu Endoh‐Yamagami

This study shows that aged human astrocytes are more neurotoxic than young ones when exposed to inflammatory stimuli, suggesting a link between aging and neurodegenerative diseases.

DOI 10.1101/2025.08.17.670762

humanexperimental assay

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