Author

Nurjahan Mehzabeen

AstraZeneca (United States)ORCID 0000-0002-7579-0292Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Andrew B. DippeliD· 1 shared Gilad KaplaniD· 1 shared Giuliana VozzaiD· 1 shared Harini ShandilyaiD· 1 shared Jeffrey A. RuffoloiD· 1 shared Jeffrey J. GrayiD· 1 shared Keith W. RickertiD· 1 shared Mark Rowland HutchinsoniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Andrew B. DippelORCID

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1 paper

Recent·Most cited

Molecular BiologymAbsPeer-reviewedJun 20, 2024

Enhancement of antibody thermostability and affinity by computational design in the absence of antigen

Mark Rowland Hutchinson, Jeffrey A. Ruffolo, Nantaporn Haskins…·Gilad Kaplan

This study uses DeepAb to design antibody variants with enhanced stability and affinity without antigen information, showing 91% and 94% improvements in thermal/colloidal stability and affinity, respectively.

22 citationstop 3%

protein sequencedeep learning