Molecular BiologymAbsPeer-reviewed
Enhancement of antibody thermostability and affinity by computational design in the absence of antigen
Mark Rowland Hutchinson, Jeffrey A. Ruffolo, Nantaporn Haskins…·Gilad Kaplan
This study uses DeepAb to design antibody variants with enhanced stability and affinity without antigen information, showing 91% and 94% improvements in thermal/colloidal stability and affinity, respectively.
22 citationstop 3%