Hippocampal multi-layered RNAseq prioritizes oligodendrocyte dysfunction over immune-driven neuroinflammation in neurolupus pathogenesis
Karim Matmat, Christian Klein, Céline Keime, Ayikoe Guy Mensah‐Nyagan, Hélène Jeltsch‐David
The paper identifies oligodendrocyte dysfunction as a key driver of NPSLE pathogenesis, contrasting with immune-driven inflammation in the hippocampus of MRL/Lpr mice.
bioRxiv · Oct 3, 2025 · PreprintNeuroscience