Author

Christian Klein

Agilent Technologies (United States)

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Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

Ankur Chakravarthy· 1 shared Beatriz Morancho· 1 shared Bernd StahliD· 1 shared Daniel D. De Carvalho· 1 shared David AllardiD· 1 shared David Roulois· 1 shared Felipe Campos de Almeida· 1 shared Gaël M. VosiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Ankur Chakravarthy

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Author profile →

2 papers

Recent·Most cited

De novo sequencing of complex glycans by ion mobility-mass spectrometry using a self-expanding reference database

Javier Sastre Toraño, Julia C. C. Vreugdenhil, Gaël M. Vos, Kevin C. Hooijschuur, Shannon Vogelaar, Christian Klein, John C. Fjeldsted, Bernd Stahl, Geert‐Jan Boons

This paper introduces a de novo sequencing method using ion mobility-mass spectrometry to identify isomeric glycans by building a self-expanding reference database from biological samples.

Nature Communications · Dec 13, 2025Peer-reviewedBiochemistry

DNA-Demethylating Agents enhance cytolytic activity of CD8+ T Cells and anti-tumor immunity

Helen Loo Yau, Ankur Chakravarthy, Felipe Campos de Almeida, David Allard, Rajat Singhania, Ilias Ettayebi, Shu Yi Shen, Tiago Medina, Parinaz Mehdipour, Beatriz Morancho, Sandra Pommey, Christian Klein, Gustavo Amarante-Mendes, David Roulois, Marcus Butler, , Daniel D. De Carvalho

The paper shows DNA demethylating agents enhance CD8+ T cell cytolytic activity and anti-tumor immunity through dsRNA sensing pathway activation.

bioRxiv · Oct 2, 2017 · PreprintCancer Biology