A shared binding interface controls Vps13 organelle-specific targeting independently of its vacuolar protein sorting function
Kevin Ryan Jeffers, Samantha Katarzyna Dziurdzik, Michael Davey, Jordan Faith Drotsky, Elizabeth Conibear
The paper shows that Vps13 binds adaptors via a shared PxP motif interface, but this interface is not required for its vacuolar protein sorting function.
Molecular Biology of the Cell · Jan 15, 2026Peer-reviewedCell Biology