Uncovering large effect loci and epistasis for lifespan in standing genetic variation in the fruit fly Drosophila melanogaster
Joost van den Heuvel, Jelle Zandveld, Klaas Vrieling, Bart A. Pannebakker, Jan E. Kammenga, Bas J. Zwaan
This study identifies six loci with significant lifespan effects and eight pairwise interactions in Drosophila melanogaster, showing that lifespan-related alleles are not necessarily selected for increased lifespan.
bioRxiv · Oct 5, 2024 · PreprintEvolutionary Biology