Jan E. Kammenga

This study shows that environmental and demographic variation additively reduce the repeatability of evolution in replicated experiments with Caenorhabditis elegans.

This study identifies six loci with significant lifespan effects and eight pairwise interactions in Drosophila melanogaster, showing that lifespan-related alleles are not necessarily selected for increased lifespan.

The paper maps eQTLs in a transgenic C. elegans RIL panel to identify genetic modifiers of alpha-synuclein aggregation and PD-related pathways.

This study investigates how developmental age variation affects eQTL patterns in C. elegans using dynamical eQTL mapping and compares it to classical methods.

The paper introduces reciprocal introgression line populations in C. elegans to study genetic interactions and complex trait architectures through QTL mapping and expression analysis.

This study identifies QTLs affecting body size and plasticity in C. elegans across different temperatures and developmental stages.

The paper examines genetic variation in the Intracellular Pathogen Response (IPR) in C. elegans, finding balancing selection in key regulators and showing haplotype-specific antiviral defense.

The paper identifies two loci on chromosome IV in C. elegans associated with OrV susceptibility, with a single nucleotide polymorphism in cul-6 contributing to the difference between strains.

The paper uses a multi-parental recombinant inbred line population in C. elegans to study gene expression variation and identifies eQTLs and trans-bands affecting gene expression.

The paper shows that conserved codon usage in highly expressed genes correlates with reduced mRNA secondary structure variability, enhancing translation efficiency and mRNA stability.

This study maps eQTL in C. elegans RILs across environments, showing higher reproducibility of local eQTL and environmental effects on eQTL micro-architecture.

WormQTL2 is a database platform that integrates and allows analysis of eQTL datasets in C. elegans to facilitate systems genetics research.

The paper measures transcriptional resilience to heat stress in C. elegans and finds it predicts long-term thermotolerance.

This study develops a multi-parent recombinant inbred line population of C. elegans to improve QTL mapping resolution and identify novel QTLs for life-history traits.

The paper identifies genetic loci controlling metabolite levels in C. elegans using recombinant inbred lines and QTL mapping.

This paper shows that TORC2 in C. elegans gut communicates feeding state to the brain, regulating developmental decisions and foraging behaviors through hormonal signaling.

This study examines gene expression changes in C. elegans during heat stress, identifying a critical time window where gene expression shifts and phenotypic damage becomes irreversible.

The paper identifies eQTLs in C. elegans that modulate Ras/MAPK signaling, revealing genetic modifiers that are not detectable in single genetic backgrounds.

The paper investigates how trans regulatory eQTL contribute to cryptic genetic variation in C. elegans under heat stress and recovery conditions.