Philippe E. Zimmern

The paper identifies a urinary E. faecalis strain with a cytolysin variant that can lyse sheep erythrocytes and inhibit urinary microbiota, suggesting a PC-independent mechanism for virulence.

This paper develops an engineered living material that continuously releases probiotic E. coli to suppress uropathogenic E. coli growth and invasion of urothelial cells in vitro and in vivo.

This study quantifies how electrical stimulation parameters of the external urethral sphincter affect urinary leakage thresholds in rats to guide neuromodulation strategies for neurogenic lower urinary tract dysfunction.

The paper investigates the invasion of bladder carcinoma cells by different phylogenetic groups of E. coli, finding that group B2 strains preferentially invade differentiated cells, with flagella playing a key role.

This study examines variation in chondroitin sulfate degradation kinetics and urea regulation among Proteus mirabilis strains, finding that urea-sensitive strains show reduced contribution of CS degradation to urovirulence.

This study examines how Enterococcus faecalis affects the transcriptome and metabolism of Escherichia coli in co-culture, revealing strain-specific responses and nutrient cross-feeding.

The paper identifies microbiome-metabolite interactions and metabolic markers associated with recurrent urinary tract infections using metagenomic and metabolomic data.

This study tracks daily and weekly urobiome fluctuations in postmenopausal women without UTI history, finding stable community structures and potential colonization resistance mechanisms.

This paper demonstrates a method to release probiotics from hydrogels using mechanical fracture, enabling sustained and controllable release of metabolically active microbes.

This study identifies the role of putrescine in pili synthesis and surface motility in E. coli, revealing a homeostatic network involving oxidative metabolism.