Dirk Scheele

A neurofunctional signature of romantic love predicts rewards on social media, effects of oxytocin and drug-cue reactivity

The paper identifies a distinct neurofunctional signature of romantic love that generalizes to social media rewards and cannabis use, and is modulated by oxytocin.

Hungry for compliments? Ghrelin is not associated with neural responses to social rewards or their pleasantness

This study investigates the relationship between ghrelin levels and neural responses to social and non-social rewards, finding no significant association with social rewards but a link to non-social rewards.

Investigation of whether oxytocin and trust play a role in placebo effects of marketing actions

This study investigates whether oxytocin and trust influence placebo effects in marketing actions but finds no evidence supporting their role.

Oxytocinergic modulation of stress-associated amygdala-hippocampus pathways in humans is mediated by serotonergic mechanisms

This study shows that oxytocin's effect on stress-related brain pathways in humans is reduced when serotonin signaling is decreased, suggesting a mediating role for serotonin.

Lonely in the dark: trauma memory and sex-specific dysregulation of amygdala reactivity to fear signals

This study finds that loneliness increases intrusive trauma memories and amygdala reactivity to fear signals in men but not women.

Alone Again: Altered Activation in the Observation Execution System during Synchronization in High Loneliness Individuals

The paper shows that high loneliness individuals have reduced movement synchronization ability and increased activation in the observation-execution system during synchronization.

Exogenous estradiol and oxytocin modulate sex differences in hippocampal reactivity and episodic memory

This study shows that estradiol and oxytocin reduce sex differences in episodic memory and hippocampal reactivity in humans, with combined treatment restoring the sex difference.

Loneliness and the social brain: how perceived social isolation impairs human interactions

This study investigates how perceived social isolation impairs trust and social interactions by analyzing neural and behavioral responses in lonely individuals.

Oxytocinergic modulation of threat-specific amygdala sensitization in humans is critically mediated by serotonergic mechanisms

This study investigates how oxytocin modulates threat-specific amygdala reactivity in humans and finds that serotonergic mechanisms are critical for this effect.

Serotonin and childhood maltreatment interact to shape brain architecture and anxious avoidant behavior, a TPH2 imaging genetics approach

The paper investigates how serotonin and childhood maltreatment interact to affect brain structure and anxious avoidant behavior using a TPH2 imaging genetics approach in humans.

Cue-reactivity in the ventral striatum characterizes heavy cannabis use, whereas reactivity in the dorsal striatum mediates dependent use

This study examines cue-reactivity in striatal regions of heavy cannabis users to differentiate between addiction-related and exposure-related adaptations.

Impaired cognitive performance under psycho-social stress in cannabis-dependent males is mediated by attenuated precuneus activity

This study finds that cannabis-dependent males show impaired cognitive performance under psycho-social stress, linked to reduced precuneus activity and altered connectivity with the dorsal medial prefrontal cortex.

Altered Reward Processing in Abstinent Dependent Cannabis Users: Social Context Matters

This study shows that cannabis dependence in men reduces reward experience during female social interaction compared to male interaction, with neural changes linked to cannabis exposure.

Shifted balance of dorsal versus ventral striatal communication with frontal reward and regulatory regions in cannabis dependence

This study uses resting state fMRI to examine a shift in striatal connectivity patterns in cannabis-dependent individuals compared to controls, finding increased ventral striatum connectivity with reward regions and reduced connectivity with regulatory regions.