Alexandra Philipsen

This study shows that spermidine supplementation improves depression symptoms by enhancing autophagy and correcting polyamine imbalances in both humans and mice.

This study finds that loneliness increases intrusive trauma memories and amygdala reactivity to fear signals in men but not women.

This study shows that estradiol and oxytocin reduce sex differences in episodic memory and hippocampal reactivity in humans, with combined treatment restoring the sex difference.

This study shows that stress enhances secretory autophagy via FKBP51, leading to increased MMP9 secretion and proBDNF cleavage to mature BDNF, linking stress adaptation to psychiatric disorders.