Author

Michela Lapi

University of MilanORCID 0000-0002-7613-2275Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Alberto Giuseppe BarbiroliiD· 1 shared Amit KumawatiD· 1 shared Anna Righetti· 1 shared Antonio Chaves-SanjuániD· 1 shared Carlo CamilloniiD· 1 shared Diane Marie Valérie BonnetiD· 1 shared Graziella MessinaiD· 1 shared Louise J. GourlayiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alberto Giuseppe BarbiroliORCID

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1 paper

Recent·Most cited

Structural bases for Nuclear Factor 1-X activation and DNA recognition. Prototypic insight into the NFI transcription factor family

Michele Tiberi, Michela Lapi, Louise J. Gourlay, Antonio Chaves-Sanjuán, Maurizio Polentarutti, Nicola Demitri, Miriam Cavinato, Diane Marie Valérie Bonnet, Valentina Taglietti, Anna Righetti, Rachele Sala, Silvia Cauteruccio, Amit Kumawat, Rosaria Russo, Alberto Giuseppe Barbiroli, , Marco Nardini

This study presents the first structural characterization of NFI-X, revealing its DNA-binding domain structure and key determinants for activity, providing a framework for understanding the NFI family's function and drug design.

bioRxiv · Mar 21, 2025 · PreprintBiochemistry