Author

Nicola Demitri

Elettra-Sincrotrone Trieste S.C.p.A.ORCID 0000-0003-0288-3233Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:structural biology· 2 Organism:Arabidopsis· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alberto Giuseppe BarbiroliiD· 1 shared Amit KumawatiD· 1 shared Andrea R. BeccariiD· 1 shared Andrea ZalianiiD· 1 shared Angela CoronaiD· 1 shared Anna Righetti· 1 shared Antonio Chaves-SanjuániD· 1 shared Barbara GiabbaiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Alberto Giuseppe BarbiroliORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintMar 21, 2025

Structural bases for Nuclear Factor 1-X activation and DNA recognition. Prototypic insight into the NFI transcription factor family

Michele Tiberi, Michela Lapi, Louise J. Gourlay…·Marco Nardini

This study presents the first structural characterization of NFI-X, revealing its DNA-binding domain structure and key determinants for activity, providing a framework for understanding the NFI family's function and drug design.

1 citation

structural biologyexperimental assay

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BiochemistryJournal of Structural Biology XPeer-reviewedDec 26, 2024

Structural and functional characterization of SidF, a possible dual substrate Aspergillus fumigatus N5-acetyl-N5-hydroxy-L-ornithine transacetylase

Thanalai Poonsiri, Jan Stránský, Nicola Demitri…·Stefano Benini

This study characterizes SidF, a transacetylase in Aspergillus fumigatus, revealing its structure and function in siderophore biosynthesis and its role in complementing SidL during iron deficiency.

3 citations

Arabidopsisstructural biology

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Molecular BiologyACS Pharmacology & Translational SciencePeer-reviewedMar 11, 2021

Identification of inhibitors of SARS-CoV-2 3CL-Pro enzymatic activity using a small molecule in-vitro repurposing screen

Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen…·Andrea Zaliani

The paper identifies 62 new inhibitors of SARS-CoV-2 3CL-Pro through a compound repurposing screen and validates their activity using X-ray crystallography.

159 citationstop 1%

experimental assaydrug response / drug discovery

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