Single-embryo and single-blastomere immunoblotting reports protein expression heterogeneity in early-stage preimplantation embryos
Elisabet Rosàs-Canyelles, Andrew J. Modzelewski, Lin He, Amy E. Herr
This study develops a microfluidic immunoblot to measure protein expression in single embryos and blastomeres, revealing heterogeneity in DICER-1 isoforms and other proteins during preimplantation development.
bioRxiv · Jun 28, 2018 · PreprintBioengineering