Author

Andrew J. Modzelewski

University of California, BerkeleyORCID 0000-0003-0698-957XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Organism:multiple species· 1 Assay:proteomics· 1

Frequent Co-Authors

Lin HeiD· 2 shared Alyssa Saito· 1 shared Amy E. HerriD· 1 shared Ana Domingo-Meulas· 1 shared Angus Lee· 1 shared Anne BitoniD· 1 shared Aparna AnandiD· 1 shared Beril Tore· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersDevelopmental Biology

Lin HeORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintAug 26, 2026

An Intronic SINE at Pou5f1 Links Hormone Signaling to Blastocyst Hatching

Youjia Guo, Hyun Hyung An, Katelyn Toohill…·Andrew J. Modzelewski

This study identifies an intronic SINE element that regulates Pou5f1/OCT4 repression in mouse trophectoderm, linking hormone signaling to blastocyst hatching and implantation.

DOI 10.64898/2026.08.25.747035

mousestatistical model

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Developmental BiologyCellPeer-reviewedOct 1, 2021

A species-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for preimplantation development

Andrew J. Modzelewski, Wanqing Shao, Jingqi Chen…·Lin He

The paper identifies a species-specific retrotransposon promoter that generates a conserved Cdk2ap1 isoform essential for preimplantation development across mammals.

117 citationstop 1%

mousemultiple species

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BioengineeringbioRxivPreprintJun 28, 2018

Single-embryo and single-blastomere immunoblotting reports protein expression heterogeneity in early-stage preimplantation embryos

Elisabet Rosàs-Canyelles, Andrew J. Modzelewski, Lin He, Amy E. Herr

This study develops a microfluidic immunoblot to measure protein expression in single embryos and blastomeres, revealing heterogeneity in DICER-1 isoforms and other proteins during preimplantation development.

DOI 10.1101/357731

mouseproteomics

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