A Toolbox for Binary and Rheostat-like Modulation of TOX Expression via Genome and Epigenome Editing in Primary Human T cells
Elaine V. Schanzer, Katharine F Vostrejs, Alexandra N Kurciska, Omar Khan, Fyodor D. Urnov
This paper develops genome and epigenome editing tools to modulate TOX expression in human T cells and shows that TOX knockout has limited transcriptomic effects.
bioRxiv · Aug 18, 2026 · PreprintMolecular Biology