Author

Alexandra N Kurciska

Innovative Genomics Institute

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Molecular Biology· 1

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

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Elaine V. SchanzeriD· 1 shared Fyodor D. UrnoviD· 1 shared Katharine F Vostrejs· 1 shared Omar KhaniD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperMolecular Biology

Elaine V. SchanzerORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintAug 18, 2026

A Toolbox for Binary and Rheostat-like Modulation of TOX Expression via Genome and Epigenome Editing in Primary Human T cells

Elaine V. Schanzer, Katharine F Vostrejs, Alexandra N Kurciska…·Fyodor D. Urnov

This paper develops genome and epigenome editing tools to modulate TOX expression in human T cells and shows that TOX knockout has limited transcriptomic effects.

DOI 10.64898/2026.08.13.744691

humanCRISPR screen

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