Yolanda Sánchez

Rho1 and Rgf3 regulate the expansion of the nuclear envelope during fission yeast mitosis/cytokinesis

This study identifies Rho1 and Rgf3's role in nuclear envelope expansion during fission yeast mitosis by modulating phospholipid synthesis via the Kennedy pathway.

Phenotype-driven identification of drug targets for post-COVID-19 anosmia

This paper identifies six potential drug targets for post-COVID-19 anosmia using a phenotype-to-gene-to-drug approach via the Phenograph knowledge graph.

Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design

This paper genomically characterizes 261 pediatric cancer patient-derived xenograft models to guide rational clinical trial design and drug development.

A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma

The paper trains a machine learning classifier on cancer transcriptomes to detect NF1 inactivation in glioblastoma, showing it can predict NF1 status based on gene expression and mutation data.