Esther R. Berko

This paper develops a mutation-independent liquid biopsy method using DNA methylation to monitor high-risk neuroblastoma through blood plasma-derived cfDNA.

The paper investigates how extrachromosomal DNA (ecDNA) inheritance mechanisms influence cancer evolution through mitotic segregation and micronuclei formation.

This paper genomically characterizes 261 pediatric cancer patient-derived xenograft models to guide rational clinical trial design and drug development.

MAD-seq detects low-level mosaic chromosomal aneuploidy using a new sequencing assay and analysis method, revealing previously unrecognized aneuploidy in public datasets.

This study identifies epigenetic dysregulation in ectodermal cells of individuals with ASD born to older mothers, suggesting a potential role for epigenetic changes in ASD pathogenesis.