Author

C. Patrick Reynolds

Texas Tech UniversityORCID 0000-0002-2827-8536Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A Herman· 1 shared A Robichaud· 1 shared Adam David DurbiniD· 1 shared Alejandro Sweet-CorderoiD· 1 shared Alvin FarreliD· 1 shared Anang A. ShelatiD· 1 shared Anthony C. BryaniD· 1 shared Apexa ModiiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A Herman

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Author profile →

2 papers

Recent·Most cited

Tabular foundation model predicts alternative lengthening of telomeres (ALT) and identifies SMARCAL1 as a target in ALT-driven cancers

Declan Bennett, Monika Wierdl, S Chakraborty, Jordan Johnson, Victoria Akingbehin, Daniel Estevez-Prado, Yuan Feng, Janeala J. Morsby, John Harper, Mohammad Ali Mohammad Nezhady, M Pan, Nicole Ocasio-Martinez, Jerrel Lewis Catlett, TB Nations, Neekesh V. Dharia, , Lillian M. Guenther

The paper develops ALTitude, a machine learning model to predict ALT status from whole genome sequencing data, identifies SMARCAL1 as a therapeutic target in ALT-driven cancers.

bioRxiv · May 28, 2026 · PreprintCancer Biology

Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design

Jo Lynne Rokita, Komal S. Rathi, Maria Cardenas, Kristen A. Upton, Joy C. Jayaseelan, Katherine L. Cross, Jacob Pfeil, Laura E. Egolf, Gregory P. Way, Alvin Farrel, Nathan M. Kendsersky, Khushbu Patel, Krutika Satish Gaonkar, Apexa Modi, Esther R. Berko, , John M. Maris

This paper genomically characterizes 261 pediatric cancer patient-derived xenograft models to guide rational clinical trial design and drug development.

Cell Reports · Nov 1, 2019Peer-reviewedGenomics