Label-free volumetric refractive-index imaging of fibrillar collagen architecture, assembly, and cell-associated remodeling
Sehyeon Lee, Wei Sun Park, Juheon Lee, J Park, Hyeoncheol Park, Eun Hyun Ahn, Deok‐Ho Kim, YongKeun Park
This paper introduces holotomography (HT) for label-free volumetric imaging of collagen architecture, showing its ability to resolve fiber morphology, orientation, and mass without exogenous labels.
bioRxiv · Jun 25, 2026 · PreprintCell Biology