J Park

This paper introduces holotomography (HT) for label-free volumetric imaging of collagen architecture, showing its ability to resolve fiber morphology, orientation, and mass without exogenous labels.

The paper presents the first single-cell immune atlas of a Mainland Southeast Asian population, showing genetic ancestry shapes innate immune profiles and highlights sex-by-ancestry interactions in immune activation.

The paper identifies SPP1 and CD44 as influencers of inflammation in preeclampsia by analyzing single-cell transcriptional profiles of placental immune cells.

DeepHOPE uses deep learning and 3D imaging to assess pluripotency in hPSCs, detecting structural changes before molecular loss of pluripotency.

This study shows that modifying ionizable lipids and formulation parameters of mRNA vaccines can enhance CD4+ T cell immunity and improve vaccine efficacy.

This study corrects a SSBP1 mutation using adenine base editors, improving mitochondrial function but with trade-offs between editing efficacy and off-target risks.