Deok‐Ho Kim

Label-free volumetric refractive-index imaging of fibrillar collagen architecture, assembly, and cell-associated remodeling

This paper introduces holotomography (HT) for label-free volumetric imaging of collagen architecture, showing its ability to resolve fiber morphology, orientation, and mass without exogenous labels.

Deep-learning-enabled morphodynamic analysis of drug responses in a biomimetic fibrin-based 3D glioblastoma invasion model

This paper develops a 3D glioblastoma model with deep learning to predict drug responses and invasion patterns.

Analysis of the phosphorylation networks characterizing distinct phenotypic states in glioblastoma cell Populations

The paper identifies phenotype-specific signaling networks in glioblastoma cells, showing that invasive spread is linked to DNA damage response and AKT-mTOR activation, with 14-3-3 proteins mediating phosphorylation and predictive phospho-site signatures for patient survival.

Expression Microdissection for use in qPCR based analysis of miRNA in a single cell type

The paper optimizes an expression microdissection method to improve miRNA yield and in vivo cell-type specificity for qPCR analysis.

Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy

The paper investigates how lamin A/C haploinsufficiency affects chromatin compartments and gene expression in human cardiomyocytes, finding limited compartmental changes despite electrophysiological and gene expression alterations.