Author

Serena Vaglietti

University of TurinORCID 0000-0002-7660-0761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Andrea AlessandriniiD· 1 shared Antonia GurgoneiD· 1 shared Ferdinando FiumaraiD· 1 shared Gregorio RagazziniiD· 1 shared Luca ColnaghiiD· 1 shared Marco Dell’OcaiD· 1 shared Maurizio GiustettoiD· 1 shared Mirella GhirardiiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Andrea AlessandriniORCID

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1 paper

Recent·Most cited

The CDKL5 kinase undergoes liquid-liquid phase separation driven by a serine-rich C-terminal region and impaired by neurodevelopmental disease-related truncations

Marco Dell’Oca, Stefania Boggio Bozzo, Serena Vaglietti, Antonia Gurgone, Vita Cardinale, Gregorio Ragazzini, Andrea Alessandrini, Luca Colnaghi, Mirella Ghirardi, Maurizio Giustetto, Ferdinando Fiumara

This study shows CDKL5 undergoes liquid-liquid phase separation driven by its C-terminal domain, and disease mutations impair this process, reducing phosphorylation of EB2.

bioRxiv · Nov 18, 2024 · PreprintMolecular Biology