This study identifies subregional cerebellar atrophy patterns in epilepsy syndromes using MRI data from 1,602 patients and 1,022 controls, finding significant volume loss in posterior lobe regions.

Epilepsia · Feb 27, 2024Peer-reviewedNeuroscience

Seizure pathways change on circadian and slower timescales in individual patients with focal epilepsy

Gabrielle M. Schroeder, Beate Diehl, Fahmida A Chowdhury, John Sidney Duncan, Jane de Tisi, Andrew J. Trevelyan, Rob J Forsyth, Andrew Jackson, Peter N. Taylor, Yujiang Wang

The paper analyzes seizure network dynamics in focal epilepsy patients, finding that seizure pathways change on circadian and slower timescales, independent of medication.

Proceedings of the National Academy of Sciences · May 4, 2020Peer-reviewedNeuroscience

Node abnormality predicts seizure outcome and relates to long-term relapse after epilepsy surgery

Nishant Sinha, Yujiang Wang, Nádia Moreira da Silva, Anna Miserocchi, Andrew W. McEvoy, Jane de Tisi, Sjoerd B. Vos, Gavin Paul Winston, John Sidney Duncan, Peter N. Taylor

The paper uses structural brain networks and clinical data to predict seizure outcomes and relapse after epilepsy surgery, finding that more abnormal nodes correlate with worse outcomes.

bioRxiv · Sep 1, 2019 · PreprintNeuroscience