E. Becker

The paper introduces a weighted pathway co-membership method for Reactome pathways, improving gene prioritization in cancer hallmarks by incorporating biological distances and hierarchical structure.

BioPAX-Explorer simplifies querying and analyzing BioPAX biological pathway data by providing an object-oriented Python framework with query capabilities and tools for data extraction and workflow development.

This study shows that Exosc10 is essential for early embryogenesis, as its knockout causes developmental arrest at the eight-cell embryo/morula transition.