Ectopic activation of the polar body extrusion pathway triggers cell fragmentation in preimplantation embryos
Diane Pelzer, Ludmilla de Plater, Peta Bradbury…·Jean‐Léon Maître
This study identifies that ectopic activation of the polar body extrusion pathway during mitosis in preimplantation embryos triggers cell fragmentation through actomyosin contractility.