Manja Thorwirth

The paper identifies ECM remodeling differences between slowly and rapidly dividing RGCs that regulate aNSC emergence and pool size through in vivo perturbation and single-cell RNA-sequencing.

The paper identifies age-related changes in cortical astrocytes, including impaired Wnt signaling and Jun transcription factors, using single-cell RNA-seq and multiome analysis in mice.

This study shows that TREM2 deficiency rescues synaptic integration and functional maturation of transplanted neurons in an inflammatory environment.

This study shows that transplanted neurons in traumatic brain injury environments form excessive but vulnerable connections, while fewer connections are formed in intact or inflamed brains.