Author

David O. Osei-Hwedieh

Massachusetts General HospitalORCID 0000-0002-7695-9643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Brad J. FortunatoiD· 1 shared Christopher HemaueriD· 1 shared Corrie PainteriD· 1 shared Damien VasseuriD· 1 shared Garyoung Gary LeeiD· 1 shared Gunsagar Singh GulatiiD· 1 shared Hunter SavignanoiD· 1 shared Ji-Heui SeoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Brad J. FortunatoORCID

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1 paper

Recent·Most cited

SNAP: Streamlined Nextflow Analysis Pipeline for Immunoprecipitation-Based Epigenomic Profiling of Circulating Chromatin

Ze Zhang, Paulo Da Silva Cordeiro, Surya B. Chhetri, Brad J. Fortunato, Zhenjie Jin, Razane El Hajj Chehade, Karl Semaan, Gunsagar Singh Gulati, Garyoung Gary Lee, Christopher Hemauer, Weiwei Bian, Shahabeddin Sotudian, Ziwei Zhang, David O. Osei-Hwedieh, Tanya E. Heim, , Sylvan C. Baca

SNAP improves classification performance for cell-free chromatin data while maintaining data retention through optimized quality filters and modular design.

bioRxiv · Dec 30, 2025 · PreprintBioinformatics