Author

Melih Ö. Celik

Charité – Universitätsmedizin BerlinORCID 0000-0002-7706-4964Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Arne ThiesiD· 1 shared Christof SchütteiD· 1 shared Christoph SteiniD· 1 shared Fatih YergöziD· 1 shared Hanna WulkowiD· 1 shared Marcus WeberiD· 1 shared Sourav RayiD· 1 shared Stefanie WinkelmanniD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperSystems Biology

Arne ThiesORCID

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1 paper

Recent·Most cited

Modelling altered signalling of G-protein coupled receptors in inflamed environment to advance drug design

Sourav Ray, Arne Thies, Vikram Sunkara, Hanna Wulkow, Melih Ö. Celik, Fatih Yergöz, Christof Schütte, Christoph Stein, Marcus Weber, Stefanie Winkelmann

The paper develops a stochastic model of GPCR function in inflamed environments and validates it with experimental data, showing that low pH has a greater impact on GPCR behavior than radicals.

bioRxiv · Oct 20, 2021 · PreprintSystems Biology