Author

Syeda Maryam Azeem

The Graduate Center, CUNYORCID 0000-0002-7712-527XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Pooja Prakash RaoiD· 2 shared Raisa Munira· 2 shared Shahana S. MahajaniD· 2 shared Adriana Haimovitz‐FriedmaniD· 1 shared Charis Herbert· 1 shared Elena Gary· 1 shared Gloria Ho· 1 shared Hadi Askarifirouzja· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Pooja Prakash RaoORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 15, 2025

EGR1 Mediates Riluzole-Induced Apoptosis in Osteosarcoma via the Yap/p73-Bax Signaling Axis

Syeda Maryam Azeem, Shraddha ChandThakuri, Pooja Prakash Rao…·Shahana S. Mahajan

This study shows Riluzole induces apoptosis in osteosarcoma by upregulating EGR1, which interacts with Yap/p73 to enhance Bax expression and promote cell death.

DOI 10.1101/2025.10.15.682608

humanproteomics

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Cancer BiologyInternational Journal of Radiation Oncology*Biology*PhysicsPeer-reviewedSep 1, 2025

Riluzole as a Dual-Targeted Radiosensitizer for Osteosarcoma: Targeting Tumor Cells and Angiogenic Vasculature to Enhance Single High Dose Radiotherapy Efficacy

Pooja Prakash Rao, Charis Herbert, Syeda Maryam Azeem…·Shahana S. Mahajan

This paper demonstrates that Riluzole enhances osteosarcoma radiosensitivity to single high dose radiotherapy by targeting both tumor cells and angiogenic vasculature.

DOI 10.1016/j.ijrobp.2025.06.3486

humanexperimental assay

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