Thomas W. McCarthy

The paper compares miRNA-mRNA profiles across human and murine AKI models to identify shared and specific molecular programs associated with different injury etiologies and biological heterogeneity.

The paper identifies altered protein translation and carboxylic acid catabolism in diabetic kidney disease using human and mouse models.

This study uses single-cell RNA sequencing to define the temporal cellular and molecular changes in the kidney during sepsis, identifying key gene expression shifts and communication failures that mark critical points in the sepsis timeline.