EFN-4/Ephrin converges with SAX-3/Robo, UNC-6/Netrin, and Heparan Sulfate Proteoglycan signaling to control MAB-5/Hox-dependent posterior Q neuroblast migration in Caenorhabditis elegans
Vedant Deepak Jain, Andrew Johannesen, Felipe Lopes Teixeira, Erik A. Lundquist
The paper identifies EFN-4/Ephrin as a key regulator of posterior Q neuroblast migration in C. elegans and shows it converges with SAX-3/Robo, UNC-6/Netrin, and HSPG signaling in this process.
PLoS Genetics · Sep 8, 2026Peer-reviewedDevelopmental Biology